Mikrovesiklar - Microvesicles - qaz.wiki

Extending gene ontology in the context of extracellular RNA

A set of exclusion ﬁlters was used in this order: number of entries for the bioﬂuid, number of ID entries for Homo sapiens, number of ID entries List of top 100 proteins that are often identified in EVs. DOWNLOAD HERE Exosomal proteomes derived from CSF, serum and plasma were obtained by accessing three online databases (ExoCarta, Vesiclepedia and EVpedia). For each database, the proteins found in exosomes were collected and a list of proteins/corresponding genes present was produced for each biofluid. Vesiclepedia：细胞外囊泡综合数据库. 导语. Vesiclepedia是一个EVs分子数据（脂质、RNA和蛋白质）的手工检索数据库，目前包含来自于过去一些年份文献中发表的341个独立研究的35264个蛋白，18718个mRNA，1772个miRNA、342个脂质条目，Apoptotic blebs凋亡小泡、Exosomes 外泌体、Microparticles 微粒体、Microvesicles 微囊泡 ExoCarta, an exosome database, provides with the contents that were identified in exosomes in multiple organisms. Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool.

read more 28/05/2015. New miRNA list mapped to Entrez Gene ID available for download. read more 24/04/2015. FunRich tool published in Proteomics.

Pancreatic extracellular communication - Chalmers Publication Library

This unique class of extracellular organelles which play pivotal role in intercellular communication are conserved across prokaryotes and eukaryotes. Further support for the role of exosomes (and possibly MVs) in mediating the systemic benefits of exercise comes from the fact that the majority of the previously reported myokines/exerkines are found in extracellular vesicles databases (Vesiclepedia and ExoCarta).

Isolering och masspektrometrianalys av extraexosomala

It is clear that there were 584 species of previously identified sEVs-associated proteins (the intersecting area in Venn diagrams) detected in sEVs isolated by the novel approach, much more than protein species of sEVs separated by UC (180) and SEC (366). TCGA. The Cancer Genome Atlas: From the analysis of over 11,000 tumors from 33 of the most prevalent forms of cancer, the Pan-Cancer Atlas provides a uniquely comprehensive, in-depth, and interconnected understanding of how, where, and why tumors arise in humans.

Among the 443 identified proteins, 334 (75.4%) proteins were found in previously published data (Figure 3B, Table S2), including the common exosomal markers CD9, CD81, flotillin and syntenin. Software The exRNA Atlas has an Application Programming Interface that can be used for programmatic access to Atlas data and metadata. More information can be found on the exRNA Atlas MORE TCGA.
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We no longer track individual seminars here –– we could not keep up! On Monday and Tuesday April 19–20, 2021, the ERCC hosted a free online workshop on exRNA data analysis. There were three target audiences: experimentalists generating exRNA-seq data, computational and data scientists who have worked with those groups to analyze their data, and other interested data scientists.

Exosomes contain peptides and several nucleic acids (microRNA [miRNA], messenger RNA [mRNA], mitochondrial DNA [mtDNA]) and are involved in intercellular/tissue exchange of their contents. An overall comparison of EVpedia with Exocarta and Vesiclepedia is shown in Tables I and II. These three web‐based repositories contain proteomic, transcriptomic and lipidomic studies of non‐mammalian eukaryotic and mammalian EVs. However, only EVpedia provides additional proteomic and lipidomic studies on prokaryotic EVs (Table I). As sources of gene product annotations in the exRNA context, ExoCarta [ 45] and Vesiclepedia [ 46] are online databases that catalogue proteins, RNAs and lipids identified specifically in exosomes and other extracellular vesicle types, respectively.
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Mikrovesiklar - Microvesicles - qaz.wiki

Vesiclepedia was built using ZOPE, an open source content management system, while Python a portable, interpreted, object oriented programming language was utilised to connect the web interface with the MySQL database. As sources of gene product annotations in the exRNA context, ExoCarta and Vesiclepedia are online databases that catalogue proteins, RNAs and lipids identified specifically in exosomes and other extracellular vesicle types, respectively.

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Extending gene ontology in the context of extracellular RNA

The new version of ExoCarta database has more than 2-fold data compared to the last release in 2012 and has new additional features including the annotation of International Society for Extracellular Vesicles (ISEV) standards and dynamic protein–protein interaction networks. Compared to the exosomal database ExoCarta , Vesiclepedia (http://www.microvesicles.org) is a compendium that catalogues proteins, RNAs, lipids and metabolites that are identified in all classes of EVs . Vesiclepedia was built using ZOPE, an open source content management system, while Python a portable, interpreted, object oriented programming language was utilised to connect the web interface with the MySQL database.